What you need to know about an Acetaminophen overdose including: what causes an overdose, signs and symptoms to look out for, and the treatment options. Tylenol in high doses can permanently damage the liver and lead to coma and death in some cases. Learn about the signs and symptoms of tylenol-related liver damage, as well as its causes. Discover how tylenol liver damage is diagnosed, and what treatment options are available. Paracetamol poisoning Synonyms Acetaminophen toxicity, paracetamol toxicity, acetaminophen poisoning, paracetamol overdose, acetaminophen overdose, Tylenol toxicity Several centers in the United States and in many other countries recommend treatment only for patients who have a serum concentration that falls above the “probable toxicity” line, which starts at 200 μg per milliliter 4 hours after ingestion. Acetaminophen (Tylenol) is a pain medicine. Acetaminophen overdose occurs when someone accidentally or intentionally takes more than the normal or recommended amount of this medicine. Acetaminophen (Tylenol) Poisoning Treatment Treatment in the emergency department depends on the condition of the person and any other medications taken. If someone is suspected of having taken an overdose but has no symptoms, the doctor may begin the following treatment: What Is Acetaminophen Toxicity? Acetaminophen (Tylenol®) toxicity is a common cause of acute liver failure in children and adolescents. Acetaminophen, also known as paracetamol and N-acetyl-p-aminophenol (APAP), is primary used for the treatment of pain and/or fever, but is also a component in numerous medications, including Percocet®, Alka. Acetaminophen (Tylenol) Poisoning Overview. Acetaminophen is one of the most common medications found in households. It is used for the treatment of pain and to lower fever. While acetaminophen toxicity is particularly common in children, adults have accounted for most of the serious and fatal cases. Acetaminophen toxicity is the most common cause of hepatic failure requiring liver transplantation in Great Britain. Find out from WebMD what to do in case a person takes too much Tylenol (acetaminophen).